Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GNRHR | P30968 | 4/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787570 | 0.88 | MAPT (0.45) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL23268090 | 0.86 | KMT2A (0.45) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL29874201 | 0.85 | CYP19A1 (0.46) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL23250037 | 0.85 | CYP19A1 (0.46) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL29873912 | 0.82 | TDP1 (0.48) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL23250124 | 0.82 | TDP1 (0.48) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL21787680 | 0.77 | MEN1 (0.50) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL30414767 | 0.76 | PTGDR2 (0.50) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL28548429 | 0.76 | PTGDR2 (0.50) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL21774713 | 0.74 | PTGS2 (0.46) | MEN1KMT2ALMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024086759-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-04-25 | — | — | WO | disclosed |