Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27426994 | 0.86 | MEN1 (0.42) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL29873912 | 0.86 | TDP1 (0.48) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL23250124 | 0.86 | TDP1 (0.48) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL21787570 | 0.83 | MAPT (0.45) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL23267876 | 0.80 | BRPF1 (0.41) | KMT2AMEN1MAPTALDH1A1CNR2 | |
| SCHEMBL21787680 | 0.78 | MEN1 (0.50) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL23045577 | 0.75 | NOD2 (0.52) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL31383470 | 0.75 | NOD2 (0.52) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL21774717 | 0.71 | CYP1A2 (0.55) | KMT2AMEN1CYP1A2MAPTALDH1A1 | |
| SCHEMBL28561811 | 0.71 | CYP19A1 (0.47) | KMT2AMEN1CYP1A2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077010-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | ARVINAS OPERATIONS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |