Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 2/20 | 0.46 |
| ▸ | PRKACG | P22612 | 2/20 | 0.46 |
| ▸ | PRKACB | P22694 | 2/20 | 0.46 |
| ▸ | NOS3 | P29474 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | NCF1 | P14598 | 2/20 | 0.34 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22531427 | 0.83 | PRKACA (0.47) | PRKACAPRKACGPRKACBKDM4EMEN1 | |
| SCHEMBL27176187 | 0.80 | PRKACA (0.45) | PRKACAPRKACGPRKACBKDM4EMEN1 | |
| SCHEMBL15741185 | 0.78 | LRRK2 (0.40) | PRKACAPRKACGPRKACBKDM4EMEN1 | |
| SCHEMBL22980341 | 0.78 | PRKACA (0.38) | PRKACAPRKACGPRKACBNOS3NOS2 | |
| SCHEMBL565899 | 0.78 | HTT (0.41) | PRKACAPRKACGPRKACBNOS3NOS2 | |
| SCHEMBL29589050 | 0.78 | PRKACA (0.44) | PRKACAPRKACGPRKACBNOS3NOS2 | |
| SCHEMBL7912645 | 0.78 | PRKACA (0.38) | PRKACAPRKACGPRKACBNOS3NOS2 | |
| SCHEMBL17212756 | 0.78 | PRKACA (0.44) | PRKACAPRKACGPRKACBKDM4EMEN1 | |
| SCHEMBL1261198 | 0.78 | NOS2 (0.54) | PRKACAPRKACGPRKACBNOS3NOS2 | |
| SCHEMBL31622333 | 0.78 | LRRK2 (0.40) | PRKACAPRKACGPRKACBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1235992-A | Water-soluble fiber-reactive dyes, processes for their preparation and their use | HOECHST AG (DE) | 1999-11-24 | — | — | CN | disclosed |
| CN-1108277-A | Water-soluble fibre-reactive dyes, their preparation and their use | HOECHST AG (DE) | 1995-09-13 | — | — | CN | disclosed |