Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 18/20 | 0.66 |
| ▸ | FGFR1 | P11362 | 10/20 | 0.58 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.58 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25162435 | 0.94 | FGFR4 (0.74) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL25162439 | 0.89 | FGFR4 (0.74) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL25162437 | 0.88 | FGFR4 (0.72) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL25162206 | 0.85 | FGFR4 (0.80) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL25162440 | 0.84 | FGFR4 (0.83) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL25162205 | 0.81 | FGFR4 (0.72) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL27428515 | 0.81 | FGFR4 (0.64) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL15434012 | 0.80 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL25162191 | 0.79 | FGFR4 (0.83) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL28683029 | 0.78 | FGFR4 (0.63) | FGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393921-A1 | NALIDINONE COMPOUND AS FGFR4 INHIBITOR AND USE THEREOF | Wenzhou Medical University (CN) | 2024-07-03 | — | — | EP | disclosed |