Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003377 | 0.84 | AAK1 (0.41) | SMN1; SMN2ALDH1A1AAK1LMNAL3MBTL1 | |
| SCHEMBL30175909 | 0.84 | AAK1 (0.41) | SMN1; SMN2ALDH1A1AAK1LMNAL3MBTL1 | |
| SCHEMBL3915767 | 0.82 | ALDH1A1 (0.42) | TSHRALDH1A1KMT2AKDM4EAAK1 | |
| SCHEMBL16096043 | 0.81 | AAK1 (0.40) | POLBSMN1; SMN2ALDH1A1AAK1LMNA | |
| SCHEMBL28896606 | 0.80 | ALDH1A1 (0.45) | POLBTSHRSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30829434 | 0.80 | ALDH1A1 (0.45) | POLBTSHRSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL21789125 | 0.80 | NR4A2 (0.41) | TSHRSMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL22000036 | 0.78 | ACLY (0.47) | POLBMEN1KMT2AL3MBTL1MTNR1A | |
| SCHEMBL20671184 | 0.78 | AAK1 (0.40) | POLBSMN1; SMN2ALDH1A1AAK1LMNA | |
| SCHEMBL30116140 | 0.78 | AAK1 (0.40) | POLBSMN1; SMN2ALDH1A1AAK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114403-C | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 2003-07-16 | — | — | CN | disclosed |
| CN-1238689-A | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-12-15 | — | — | CN | disclosed |