Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14019463 | 0.81 | USP2 (0.41) | USP2TSHR | |
| SCHEMBL23466099 | 0.78 | SLC22A1 (0.34) | USP2 | |
| SCHEMBL12464686 | 0.76 | OPRM1 (0.33) | — | |
| SCHEMBL90746 | 0.75 | PARP1 (0.32) | — | |
| SCHEMBL14586042 | 0.75 | — | — | |
| SCHEMBL22663697 | 0.75 | USP2 (0.32) | USP2 | |
| SCHEMBL14413879 | 0.74 | USP2 (0.33) | USP2 | |
| SCHEMBL10305806 | 0.73 | HPGD (0.34) | TSHR | |
| SCHEMBL10447437 | 0.73 | HPGD (0.34) | TSHR | |
| SCHEMBL10447629 | 0.73 | HPGD (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024076674-A1 | HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF | AMGEN INC. (US) | 2024-04-11 | — | — | WO | disclosed |