SCHEMBL27430385

SCHEMBL27430385

COC([SiH3])(NC(=O)/C=C\C(N)=O)C(C)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
HTT P42858 2/20 0.36
GAA P10253 1/20 0.36
DDAH1 O94760 1/20 0.33
LMNA P02545 1/20 0.31
MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27448698 0.80
SCHEMBL28173064 0.74
SCHEMBL2292719 0.66 ALDH1A1 (0.30) ALDH1A1
SCHEMBL56082 0.65 ALDH1A1 (0.33) ALDH1A1
SCHEMBL27485183 0.64
SCHEMBL13058268 0.63 MAPT (0.42) ALDH1A1MAPTHTTGAADDAH1
Hydrochloric Acid SCHEMBL27536628 0.63
SCHEMBL14771182 0.61
SCHEMBL5156777 0.61
SCHEMBL9594567 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1113075-A Brittle oxide substrates strengthened by cross-linkable silanes ATOCHEM NORTH AMERICA ELF (US) 1995-12-06 CN claimed
CN-1113075-A Brittle oxide substrates strengthened by cross-linkable silanes ATOCHEM NORTH AMERICA ELF (US) 1995-12-06 CN disclosed