Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Xylene SCHEMBL29869347 | 0.89 | TSHR (0.47) | NAPRTKDM4EGAATSHRCYP1A2 | |
| Toluic Acid SCHEMBL28867183 | 0.84 | TSHR (0.50) | NAPRTKDM4EGAAMAPTALDH1A1 | |
| SCHEMBL4683307 | 0.82 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDTSHR | |
| Acetic Acid SCHEMBL5593609 | 0.81 | ALDH1A1 (0.47) | NAPRTALDH1A1HPGDTSHR | |
| Methyl Alcohol SCHEMBL9135360 | 0.81 | TSHR (0.53) | NAPRTKDM4EGAAMAPTTSHR | |
| Toluic Acid SCHEMBL4152 | 0.81 | ALDH1A1 (0.65) | NAPRTKDM4EMAPTMYCALDH1A1 | |
| SCHEMBL28298 | 0.81 | — | — | |
| SCHEMBL21114388 | 0.81 | TSHR (0.57) | NAPRTKDM4EGAAMAPTTSHR | |
| Toluic Acid SCHEMBL6571818 | 0.81 | ALDH1A1 (0.65) | NAPRTKDM4EMAPTMYCALDH1A1 | |
| SCHEMBL10141202 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1112343-C | Skin lightening compositions | CHILDREN S MEDICAL CT (US) | 2003-06-25 | — | — | CN | disclosed |
| CN-1146196-A | Skin lightening compositions | PROCTER & GAMBLE (US) | 1997-03-26 | — | — | CN | disclosed |