Toluic Acid

Toluic Acid

SCHEMBL6571818

Cc1ccccc1C(=O)O.c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.65
ALOX15 P16050 1/20 0.65
HPGD P15428 4/20 0.64
KDM4E B2RXH2 3/20 0.64
HSD17B10 Q99714 2/20 0.64
MYC P01106 2/20 0.63
CYP3A4 P08684 2/20 0.59
CYP2C9 P11712 2/20 0.59
KMT2A Q03164 2/20 0.59
POLB P06746 1/20 0.57
ERCC5 P28715 1/20 0.55
FEN1 P39748 1/20 0.55
NAPRT Q6XQN6 2/20 0.55
AKR1C3 P42330 2/20 0.55
MEN1 O00255 1/20 0.55
AKR1B10 O60218 1/20 0.55
TRPA1 O75762 1/20 0.55
ABCB11 O95342 1/20 0.55
DHFR P00374 1/20 0.55
LMNA P02545 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluic Acid SCHEMBL4152 1.00 ALDH1A1 (0.65) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL28037745 1.00 ALDH1A1 (0.65) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL148201 1.00 ALDH1A1 (0.65) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL29414127 1.00 ALDH1A1 (0.65) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL5748070 0.97 ALDH1A1 (0.62) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL6913552 0.97 ALDH1A1 (0.62) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL6913659 0.97 ALDH1A1 (0.62) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL4730975 0.97 ALDH1A1 (0.62) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL6915532 0.97 ALDH1A1 (0.62) ALDH1A1ALOX15HPGDKDM4EHSD17B10
Toluic Acid SCHEMBL6113300 0.97 ALDH1A1 (0.62) ALDH1A1ALOX15HPGDKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970745-B1 Catalytic system and method for coupling of aromatic compounds INVISTA TECH SARL (CH) 2004-11-03 EP claimed
CN-106632918-B Block copolymer and related photo-corrosion-resisting agent composition and the method for forming electronic device 罗门哈斯电子材料有限责任公司 2019-08-13 CN disclosed
CN-106243357-B It can the siliceous anti-reflection agent peelled off of wet type 罗门哈斯电子材料有限责任公司 2019-07-23 CN disclosed
CN-109675449-A The preparation method of the extremely low pressure aromatic polyamide base complex reverse osmosis membrane of high separability energy 自然资源部天津海水淡化与综合利用研究所 2019-04-26 CN disclosed
CN-106632918-A Block copolymer and associated photoresist composition and method of forming an electronic device 罗门哈斯电子材料有限责任公司 2017-05-10 CN disclosed