Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510198 | 0.81 | AKR1C3 (0.46) | SRCALDH1A1L3MBTL1ACHEKDM4E | |
| SCHEMBL1424025 | 0.73 | ACHE (0.47) | SRCALDH1A1L3MBTL1ACHEKDM4E | |
| SCHEMBL27607395 | 0.73 | POLB (0.48) | SRCALDH1A1L3MBTL1ACHERAB9A | |
| SCHEMBL28402652 | 0.72 | AKR1C3 (0.46) | ALDH1A1L3MBTL1ACHETDP1 | |
| SCHEMBL28564626 | 0.69 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1NPC1RAB9A | |
| SCHEMBL4619827 | 0.69 | MEN1 (0.45) | ALDH1A1L3MBTL1LPAR1LMNA | |
| SCHEMBL25268149 | 0.69 | F2 (0.40) | ACHE | |
| SCHEMBL10519437 | 0.69 | POLB (0.43) | L3MBTL1CCKARLMNASMN1; SMN2 | |
| SCHEMBL9669772 | 0.69 | TSHR (0.44) | L3MBTL1SMN1; SMN2 | |
| SCHEMBL10767353 | 0.69 | AKR1C3 (0.48) | ALDH1A1L3MBTL1ACHETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1129604-C | Amino acid derivatives and their use as thrombin inhibitors | ASTRA AB (SE) | 2003-12-03 | — | — | CN | disclosed |
| CN-1226895-A | Amino acid derivatives and their use as thrombin inhibitors | ASTRA AB (SE) | 1999-08-25 | — | — | CN | disclosed |