Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27432394 | 0.82 | NR1H2 (0.45) | POLBNR1H2HTTCHRM2CHRM4 | |
| SCHEMBL27433296 | 0.81 | CHRM2 (0.46) | POLBNR1H2HTTCHRM2CHRM4 | |
| SCHEMBL27432029 | 0.81 | NR1H2 (0.44) | POLBNR1H2HTTCHRM2CHRM4 | |
| SCHEMBL20139779 | 0.76 | TSHR (0.62) | MEN1KMT2APOLBNR1H2HTT | |
| SCHEMBL5935857 | 0.75 | ADORA1 (0.43) | MEN1KMT2APOLBTP53NR1H2 | |
| SCHEMBL4399135 | 0.75 | ADORA1 (0.43) | MEN1KMT2APOLBTP53NR1H2 | |
| SCHEMBL5935870 | 0.75 | ADORA1 (0.43) | MEN1KMT2APOLBTP53NR1H2 | |
| SCHEMBL27433186 | 0.74 | KLKB1 (0.38) | POLBNR1H2HTTCHRM2CHRM4 | |
| SCHEMBL27240311 | 0.73 | NR1H2 (0.47) | MEN1KMT2APOLBTP53NR1H2 | |
| SCHEMBL19735949 | 0.73 | ADORA1 (0.47) | MEN1KMT2APOLBTP53NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638455-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024138048-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024138048-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2024-06-27 | — | — | WO | disclosed |