Urea

Urea

SCHEMBL27433482

N#CC#N.N#CN.NC(N)=O

nearest known ligand 0.50

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
ALDH1A1 P00352 1/20 0.50
OR51E2 Q9H255 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MCL1 Q07820 1/20 0.42
CYP1A2 P05177 1/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
THPO P40225 1/20 0.38
ACHE P22303 1/20 0.36
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
LDHA P00338 1/20 0.31
LDHB P07195 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL11147505 0.96
Urea SCHEMBL3019391 0.92
Urea SCHEMBL17075286 0.91
Urea SCHEMBL28017024 0.88 LMNA (0.46) LMNAALDH1A1OR51E2TDP1MCL1
Urea SCHEMBL27384961 0.88
Urea SCHEMBL27943587 0.87
Urea SCHEMBL27439683 0.87
Urea SCHEMBL28000230 0.87 LMNA (0.55) LMNAALDH1A1OR51E2TDP1MCL1
Carbamic Acid SCHEMBL27769573 0.83
Phosphoric Acid SCHEMBL29096280 0.82 ALDH1A1 (0.40) LMNAALDH1A1OR51E2TDP1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104927352-A Treatment process for engineering plastic for busways KINGSHORE NEW RESOURCES ELECTRIC JIANGSU CO LTD 2015-09-23 CN claimed
CN-104927352-A Treatment process for engineering plastic for busways KINGSHORE NEW RESOURCES ELECTRIC JIANGSU CO LTD 2015-09-23 CN disclosed
CN-104736581-A Photocurable silicone gel composition THREE BOND FINE CHEMICAL CO LTD 2015-06-24 CN disclosed
CN-101440252-A High bearing antifriction nano-coating LANZHOU INST CHEM PHYSICS CAS (CN) 2009-05-27 CN disclosed
CN-1495232-A Fire-resistant resin composition and formed product ����贻�ѧ��ҵ��ʽ���� 2004-05-12 CN disclosed
CN-1123600-C PET recycled resin composition and molded article thereof, flame-retardant resin composition and molded article thereof DAICEL CHEM (JP) 2003-10-08 CN disclosed
CN-1293697-A PET recycled resin composition and molded article thereof, flame-retardant resin composition and molded article thereof DAICEL CHEMIAL IND LTD (JP) 2001-05-02 CN disclosed