SCHEMBL27433562

SCHEMBL27433562

C=C(C)C(=O)OCCC[Si](C)(O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.47
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
TSHR P16473 5/20 0.44
THRB P10828 1/20 0.38
ELANE P08246 1/20 0.36
MAPT P10636 2/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3101732 0.87 TDP1 (0.48) TDP1POLBAPEX1HTTTSHR
SCHEMBL26282469 0.87 TDP1 (0.48) TDP1POLBAPEX1HTTTSHR
SCHEMBL17373022 0.85 TDP1 (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL13488577 0.85 TDP1 (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL10629482 0.85 TDP1 (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL8962436 0.84 TDP1 (0.46) TDP1POLBAPEX1HTTTSHR
SCHEMBL394445 0.84 TDP1 (0.43) TDP1POLBAPEX1HTTTSHR
SCHEMBL4860744 0.83 TDP1 (0.45) TDP1POLBAPEX1HTTTSHR
SCHEMBL9764044 0.83 TDP1 (0.45) TDP1POLBAPEX1HTTTSHR
SCHEMBL4807093 0.83 TDP1 (0.47) TDP1POLBAPEX1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024130604-A1 ORGANOSILOXANE MONOMER, INK COMPOSITION AND PREPARATION METHOD THEREFOR, FLEXIBLE SEMICONDUCTOR DEVICE, AND THIN FILM ENCAPSULATION METHOD THEREFOR 深圳市首骋新材料科技有限公司 2024-06-27 WO disclosed