SCHEMBL4860744

SCHEMBL4860744

C=C(C)C(=O)OCCC[Si](C)(OC)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.45
POLB P06746 1/20 0.45
APEX1 P27695 1/20 0.45
HTT P42858 1/20 0.45
TSHR P16473 4/20 0.42
THRB P10828 1/20 0.36
ELANE P08246 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
L3MBTL1 Q9Y468 3/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPK1 P28482 1/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13863107 0.88 TDP1 (0.44) TDP1POLBAPEX1HTTTSHR
SCHEMBL17123277 0.87 TDP1 (0.43) TDP1POLBAPEX1HTTTSHR
SCHEMBL26282491 0.87 TDP1 (0.43) TDP1POLBAPEX1HTTTSHR
SCHEMBL4855177 0.87 TSHR (0.43) TDP1POLBAPEX1HTTTSHR
SCHEMBL675776 0.85 TDP1 (0.46) TDP1POLBAPEX1HTTTSHR
SCHEMBL15404813 0.85 TDP1 (0.46) TDP1POLBAPEX1HTTTSHR
SCHEMBL26282522 0.85 TDP1 (0.41) TDP1POLBAPEX1HTTTSHR
SCHEMBL26282469 0.85 TDP1 (0.48) TDP1POLBAPEX1HTTTSHR
SCHEMBL3101732 0.85 TDP1 (0.48) TDP1POLBAPEX1HTTTSHR
SCHEMBL27433562 0.83 TDP1 (0.47) TDP1POLBAPEX1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220119692-A1 DUST SUPPRESSION COMPOSITIONS AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2022-04-21 US disclosed
US-11292940-B2 Polymeric adhesive layers as ceramic precursors 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-04-05 US disclosed
US-11285702-B2 Siloxane-based adhesive layers as ceramic precursors 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-03-29 US disclosed
US-10947396-B2 Curable antifouling composition, method of use, and articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-03-16 US disclosed
US-20190352542-A1 POLYMERIC ADHESIVE LAYERS AS CERAMIC PRECURSORS 3M INNOVATIVE PROPERTIES COMPANY 2019-11-21 US disclosed
US-20190300634-A1 DUST SUPPRESSION COMPOSITIONS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY 2019-10-03 US disclosed
US-20190218425-A1 SILOXANE-BASED ADHESIVE LAYERS AS CERAMIC PRECURSORS 3M INNOVATIVE PROPERTIES COMPANY 2019-07-18 US disclosed
EP-3458487-A1 DUST SUPPRESSION COMPOSITIONS AND METHODS 3M Innovative Properties Company (US) 2019-03-27 EP disclosed
WO-2017200988-A1 DUST SUPPRESSION COMPOSITIONS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-11-23 WO disclosed
US-20160312040-A1 Curable Antifouling Composition, Method of Use, and Articles 3M INNOVATIVE PROPERTIES COMPANY 2016-10-27 US disclosed
EP-2920216-B1 CURABLE ANTIFOULING COMPOSITION, METHOD OF USE, AND ARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2016-09-21 EP disclosed
EP-2920216-A1 CURABLE ANTIFOULING COMPOSITION, METHOD OF USE, AND ARTICLES 3M Innovative Properties Company (US) 2015-09-23 EP disclosed
WO-2014078195-A1 CURABLE ANTIFOULING COMPOSITION, METHOD OF USE, AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-05-22 WO disclosed
EP-2370536-B1 COATING COMPOSITION 3M INNOVATIVE PROPERTIES CO (US) 2013-11-06 EP disclosed
US-7345120-B2 Moisture cure non-isocyanate acrylic coatings TSANG, ESQ., VIVIEN Y. 2008-03-18 US disclosed
US-20060194921-A1 Moisture cure non-isocyanate acrylic coatings TSANG, ESQ., VIVIEN Y. 2006-08-31 US disclosed
US-7074856-B2 Moisture cure non-isocyanate acrylic coatings THE SHERWIN-WILLIAMS COMPANY (US) 2006-07-11 US disclosed
EP-1581599-A2 MOISTURE CURE NON-ISOCYANATE ACRYLIC COATINGS The Sherwin-Williams Company (US) 2005-10-05 EP disclosed
WO-2004058906-A2 MOISTURE CURE NON-ISOCYANATE ACRYLIC COATINGS THE SHERWIN-WILLIAMS COMPANY (US) 2004-07-15 WO disclosed
US-20040122183-A1 Moisture cure non-isocyanate acrylic coatings SHERWIN-WILLIAMS COMPANY, THE 2004-06-24 US disclosed