Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4807093 | 0.87 | TDP1 (0.47) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL9715814 | 0.87 | TDP1 (0.47) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL26282469 | 0.86 | TDP1 (0.48) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL3101732 | 0.86 | TDP1 (0.48) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL27433562 | 0.84 | TDP1 (0.47) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL13488577 | 0.84 | TDP1 (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL17373022 | 0.84 | TDP1 (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL10629482 | 0.84 | TDP1 (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL4860744 | 0.82 | TDP1 (0.45) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL9764044 | 0.82 | TDP1 (0.45) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554706-A | LOW TEMPERATURE LIQUID CRYSTALS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-09-10 | — | — | US | disclosed |
| EP-0695770-A1 | COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1996-02-07 | — | — | EP | disclosed |
| US-5098981-A | POLYORGANOSILOXANE | CHISSO CORPORATION (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0349920-A2 | Polyorganosiloxane | Chisso Corporation (JP) | 1990-01-10 | — | — | EP | disclosed |