Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27497370 | 0.82 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1SMN1; SMN2MAPTCYP1A1 | |
| Benzene SCHEMBL3889416 | 0.82 | ALDH1A1 (0.75) | ALDH1A1TSHRTP53LMNAHTT | |
| Toluene SCHEMBL9712043 | 0.81 | TSHR (0.58) | ALDH1A1SMN1; SMN2ADORA2AADORA1TSHR | |
| Biphenyl SCHEMBL29177753 | 0.80 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1CYP1A2TAAR1TSHR | |
| Naphthalene SCHEMBL27435552 | 0.80 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MAPTCYP1A1CYP1A2 | |
| Biphenyl SCHEMBL29145978 | 0.79 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPTCYP1A1CYP1A2 | |
| Biphenyl SCHEMBL28931658 | 0.79 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPTCYP1A1CYP1A2 | |
| Biphenyl SCHEMBL1153864 | 0.79 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPTCYP1A1CYP1A2 | |
| Aniline SCHEMBL11064117 | 0.79 | TSHR (0.55) | ALDH1A1L3MBTL1MAPTCYP1A2TAAR1 | |
| Ethylbenzene SCHEMBL27561282 | 0.79 | TP53 (0.70) | ALDH1A1SMN1; SMN2MAPTCYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101575297-B | Preparation method of N-methyl-3,3-diphenylpropylamine | UNIV SHAOXING | 2012-12-05 | — | — | CN | claimed |
| CN-101575297-A | Preparation method of N-methyl-3,3-diphenylpropylamine | UNIV SHAOXING (CN) | 2009-11-11 | — | — | CN | claimed |
| CN-109438512-A | The preparation method of a kind of aromatic alkyl phosphorous oxide type compound | 湖南大学 | 2019-03-08 | — | — | CN | disclosed |
| CN-101652363-B | Thiazolyl compounds useful as kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2013-04-17 | — | — | CN | disclosed |
| CN-101575297-B | Preparation method of N-methyl-3,3-diphenylpropylamine | UNIV SHAOXING | 2012-12-05 | — | — | CN | disclosed |
| CN-101282949-B | Azole and thiazole derivatives and uses thereof | ARGENTA DISCOVERY LTD | 2012-05-23 | — | — | CN | disclosed |
| CN-101652363-A | Thiazolyl compounds as kinase inhibitor | SQUIBB BRISTOL MYERS CO US | 2010-02-17 | — | — | CN | disclosed |
| CN-101575297-A | Preparation method of N-methyl-3,3-diphenylpropylamine | UNIV SHAOXING (CN) | 2009-11-11 | — | — | CN | disclosed |
| CN-101282949-A | Azole and thiazole derivatives and their use | ARGENTA DISCOVERY LTD (GB) | 2008-10-08 | — | — | CN | disclosed |
| CN-1123564-C | Anti-inflammatory compounds | ORTHO MCNEIL PHARMACEUTICAL CO (US) | 2003-10-08 | — | — | CN | disclosed |
| CN-1373744-A | Method for producing 2-hydroxycarboxylic acid esters | BASF AG (DE) | 2002-10-09 | — | — | CN | disclosed |
| CN-1249742-A | Anti-inflammatory compounds | ORTHO MCNEIL PHARMACEUTICAL CO (US) | 2000-04-05 | — | — | CN | disclosed |