SCHEMBL27433839

SCHEMBL27433839

CC(=O)NC1[C@@H](OCCCN)OC(CO[C@]2(C)C[C@@H](O)[C@@H](NC(C)=O)C([C@H](O)[C@H](O)CO)O2)[C@H](O)[C@@H]1O

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ SIGLEC7 Q9Y286 6/20 0.52
▸ MAG P20916 6/20 0.48
▸ MAPK1 P28482 1/20 0.43
▸ SELE P16581 2/20 0.39
▸ SELL P14151 1/20 0.38
▸ SELP P16109 1/20 0.38
▸ CD22 P20273 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18934784 0.86 MAG (0.47) SIGLEC7MAGSELLSELPCD22
SCHEMBL14819216 0.86 MAG (0.47) SIGLEC7MAGSELLSELPCD22
SCHEMBL17897325 0.86 SIGLEC7 (0.66) SIGLEC7MAGSELLSELPCD22
SCHEMBL17889795 0.86 SIGLEC7 (0.66) SIGLEC7MAGSELLSELPCD22
SCHEMBL16377870 0.82 SIGLEC7 (0.66) SIGLEC7MAGSELLSELPCD22
SCHEMBL20193276 0.82 SIGLEC7 (0.66) SIGLEC7MAGSELLSELPCD22
SCHEMBL12223144 0.81 SIGLEC7 (0.73) SIGLEC7MAGSELESELLSELP
SCHEMBL15706045 0.81 SIGLEC7 (0.73) SIGLEC7MAGSELESELLSELP
SCHEMBL12223230 0.81 SIGLEC7 (0.73) SIGLEC7MAGSELESELLSELP
SCHEMBL17897142 0.80 SIGLEC7 (0.59) SIGLEC7MAGMAPK1SELLSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216510-A1 CHIMERIC ANTIGEN RECEPTORS TO SIALYL-TN GLYCAN ANTIGEN UNIV RAMOT (IL) 2024-07-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216510-A1 CHIMERIC ANTIGEN RECEPTORS TO SIALYL-TN GLYCAN ANTIGEN SIGLEC7, CD47, SIGLEC9 SIGLEC7 1/4885MAG 337/4885MAPK1 4256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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