SCHEMBL27434174

SCHEMBL27434174

CC=C(P)C(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 13/20 0.56
CES1 P23141 12/20 0.56
RAB9A P51151 1/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
XBP1 P17861 1/20 0.45
ATM Q13315 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
ALDH1A1 P00352 2/20 0.44
TSHR P16473 2/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
AKT1 P31749 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14433197 0.80 CES2 (0.68) CES2CES1RAB9ALMNAMAPT
Benzil SCHEMBL9180893 0.78 CES2 (0.74) CES2CES1RAB9ALMNAMAPT
Benzil SCHEMBL4832229 0.75 CES2 (0.88) CES2CES1RAB9ALMNAMAPT
Benzil SCHEMBL27655380 0.75 CES2 (0.88) CES2CES1RAB9ALMNAMAPT
SCHEMBL8734925 0.74 CES2 (0.59) CES2CES1RAB9ALMNAMAPT
SCHEMBL8734921 0.74 CES2 (0.59) CES2CES1RAB9ALMNAMAPT
SCHEMBL9682043 0.74 CES2 (0.62) CES2CES1RAB9ALMNAMAPT
SCHEMBL4954899 0.74 CES2 (0.62) CES2CES1RAB9ALMNAMAPT
Benzil SCHEMBL66 0.74 CES2 (1.00) CES2CES1RAB9ALMNAMAPT
Benzil SCHEMBL2156589 0.74 CES2 (1.00) CES2CES1RAB9ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110300769-A Manufacturing method, water-dispersed composition, liquid composite, resin combination and the resin cured matter of poly- carbodiimide composition, poly- carbodiimide composition 三井化学株式会社 2019-10-01 CN disclosed
CN-110062798-A Two-solution curing type adhesive composite, laminated film and its manufacturing method 三井化学株式会社 2019-07-26 CN disclosed
CN-1123814-A Method for reducing microfoam in a spray-applied waterborne composition ROHM & HAAS (US) 1996-06-05 CN disclosed