Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.68 |
| ▸ | PARP1 | P09874 | 18/20 | 0.59 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.47 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27434643 | 0.88 | TIPARP (0.55) | TIPARPPARP1 | |
| SCHEMBL27434535 | 0.84 | PARP1 (0.72) | PARP1 | |
| SCHEMBL27434490 | 0.81 | PARP1 (0.67) | TIPARPPARP1PARP2PARP3TNKS | |
| SCHEMBL25270477 | 0.81 | TIPARP (1.00) | TIPARPPARP1 | |
| SCHEMBL27434532 | 0.80 | PARP1 (0.58) | PARP1PARP2PARP3TNKSPARP6 | |
| SCHEMBL29987574 | 0.79 | PARP1 (0.55) | TIPARPPARP1PARP2PARP3TNKS | |
| SCHEMBL27077681 | 0.79 | PARP1 (0.55) | TIPARPPARP1PARP2PARP3TNKS | |
| SCHEMBL30165098 | 0.79 | TIPARP (0.75) | TIPARPPARP1 | |
| SCHEMBL24968300 | 0.79 | TIPARP (0.75) | TIPARPPARP1 | |
| SCHEMBL27446352 | 0.79 | TIPARP (0.60) | TIPARPPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217968-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-07-04 | — | — | US | disclosed |
| US-20240217968-A1 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217968-A1 | PHARMACEUTICAL COMPOUND | F11, F12, ZYX | TIPARP 4717/4885PARP1 1174/4885PARP2 1923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.