SCHEMBL27434841

SCHEMBL27434841

CCC(=O)OC1CC(CC)CCN1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.39
CHRM4 P08173 2/20 0.39
CHRM1 P11229 2/20 0.39
CHRM3 P20309 2/20 0.39
ARG1 P05089 1/20 0.33
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
THRB P10828 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIA1 P42261 1/20 0.31
GRIA2 P42262 1/20 0.31
GRIA3 P42263 1/20 0.31
GRIA4 P48058 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28498359 0.81 CHRM2 (0.40) CHRM2CHRM4CHRM1CHRM3CYP19A1
SCHEMBL27413130 0.81 CHRM2 (0.40) CHRM2CHRM4CHRM1CHRM3CYP19A1
SCHEMBL27356886 0.77 CHRM2 (0.44) CHRM2CHRM4CHRM1CHRM3ARG1
SCHEMBL27505359 0.75 CHRM2 (0.42) CHRM2CHRM4CHRM1CHRM3SLC6A3
Hydrochloric Acid SCHEMBL2084227 0.75 CHRM2 (0.42) CHRM2CHRM4CHRM1CHRM3MEN1
SCHEMBL3770125 0.75 CHRM2 (0.42) CHRM2CHRM4CHRM1CHRM3SLC6A3
SCHEMBL29068676 0.74 CHRM2 (0.41) CHRM2CHRM4CHRM1CHRM3MEN1
SCHEMBL5609380 0.72
SCHEMBL27873424 0.72 CYP19A1 (0.45) CHRM2CHRM4CHRM1CHRM3ALDH1A1
SCHEMBL10677338 0.71 ALDH1A1 (0.33) ARG1ALDH1A1DRD3SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1100143-A Enzymatic resolution of 2-piperidinecarboxylic acid alkyl esters and use of the products obtained SYNTHELABO (FR) 1995-03-15 CN disclosed