SCHEMBL28498359

SCHEMBL28498359

CCC(=O)O[C@@H]1C[C@H](C)CCN1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.40
CHRM4 P08173 2/20 0.40
CHRM1 P11229 2/20 0.40
CHRM3 P20309 2/20 0.40
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27413130 1.00 CHRM2 (0.40) CHRM2CHRM4CHRM1CHRM3CYP19A1
SCHEMBL27434841 0.81 CHRM2 (0.39) CHRM2CHRM4CHRM1CHRM3CYP19A1
SCHEMBL7297987 0.80 L3MBTL1 (0.32)
SCHEMBL9568980 0.80 ALDH1A1 (0.38)
Hydrochloric Acid SCHEMBL16774678 0.79 L3MBTL1 (0.31)
SCHEMBL27356886 0.78 CHRM2 (0.44) CHRM2CHRM4CHRM1CHRM3
Hydrochloric Acid SCHEMBL2084227 0.77 CHRM2 (0.42) CHRM2CHRM4CHRM1CHRM3
SCHEMBL27505359 0.77 CHRM2 (0.42) CHRM2CHRM4CHRM1CHRM3
SCHEMBL3770125 0.77 CHRM2 (0.42) CHRM2CHRM4CHRM1CHRM3
SCHEMBL29068676 0.75 CHRM2 (0.41) CHRM2CHRM4CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111961114-A Argatroban intermediate and preparation method and application thereof 扬州中宝药业股份有限公司 2020-11-20 CN claimed
CN-111961114-A Argatroban intermediate and preparation method and application thereof 扬州中宝药业股份有限公司 2020-11-20 CN disclosed
CN-111961114-A Argatroban intermediate and preparation method and application thereof 扬州中宝药业股份有限公司 2020-11-20 CN disclosed