SCHEMBL27435005

SCHEMBL27435005

COc1c(F)cc2c(c1C(=O)O)OCCN2Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.42
MAPT P10636 2/20 0.39
LMNA P02545 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
BRD4 O60885 1/20 0.39
AR P10275 1/20 0.37
ACACB O00763 1/20 0.37
TSHR P16473 1/20 0.36
SIGMAR1 Q99720 1/20 0.35
POLB P06746 1/20 0.34
CCR2 P41597 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27435528 0.88 KCNA3 (0.41) KCNA3BRD4ACACBTSHRCCR2
SCHEMBL27434074 0.82 AR (0.41) BRD4ARACACBTSHRSIGMAR1
SCHEMBL27435254 0.80 TP53 (0.42) MAPTCCR2MEN1KMT2A
SCHEMBL27435508 0.80 DRD3 (0.41) KCNA3MAPTLMNABRD4AR
SCHEMBL30954067 0.80 TP53 (0.42) MAPTCCR2MEN1KMT2A
SCHEMBL27434065 0.80 ALDH1A1 (0.39) MAPTLMNANPSR1BRD4AR
SCHEMBL30954082 0.79 RXFP1 (0.36) KCNA3MAPTLMNAPOLBMEN1
SCHEMBL27433248 0.79 RXFP1 (0.36) KCNA3MAPTLMNAPOLBMEN1
SCHEMBL30954054 0.79 KCNA3 (0.43) KCNA3TSHRPOLBCCR2MEN1
SCHEMBL27435374 0.79 KCNA3 (0.43) KCNA3TSHRPOLBCCR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP claimed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO claimed
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed