SCHEMBL27435508

SCHEMBL27435508

COC(=O)c1c(OC)c(Cl)cc2c1OCCN2Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 4/20 0.41
DRD2 P14416 2/20 0.41
KCNA3 P22001 1/20 0.39
ACACB O00763 1/20 0.38
ALDH1A1 P00352 4/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.38
BRD4 O60885 1/20 0.38
AR P10275 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
PKM P14618 1/20 0.38
TP53 P04637 1/20 0.38
ROCK2 O75116 1/20 0.37
ROCK1 Q13464 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27435528 0.92 KCNA3 (0.41) DRD3DRD2KCNA3ACACBALDH1A1
SCHEMBL27435364 0.91 KCNA3 (0.42) DRD3DRD2KCNA3ALDH1A1TSHR
SCHEMBL27435244 0.91 TP53 (0.43) ALDH1A1MEN1KMT2ATSHRMAPT
SCHEMBL27434065 0.89 ALDH1A1 (0.39) ACACBALDH1A1MEN1KMT2ATSHR
SCHEMBL27435408 0.87 HSP90AA1 (0.40) DRD3DRD2ALDH1A1MEN1KMT2A
SCHEMBL30954135 0.86 POLB (0.44) ALDH1A1MEN1KMT2ATSHRGAA
SCHEMBL27433845 0.86 POLB (0.44) ALDH1A1MEN1KMT2ATSHRGAA
SCHEMBL27435327 0.86 DRD2 (0.40) DRD3DRD2MEN1KMT2ALMNA
SCHEMBL30954067 0.83 TP53 (0.42) ALDH1A1MEN1KMT2AMAPTTP53
SCHEMBL27435254 0.83 TP53 (0.42) ALDH1A1MEN1KMT2AMAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed