Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27513808 | 0.83 | IGF1R (0.54) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27513125 | 0.81 | KCNH2 (0.53) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27432685 | 0.81 | IGF1R (0.50) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL6474949 | 0.81 | HTR1A (0.52) | MAPTNPY1RHTTNPY2RSMN1; SMN2 | |
| SCHEMBL27514492 | 0.80 | HTR1A (0.62) | MAPTMEN1KMT2AKCNH2DRD2 | |
| SCHEMBL27513126 | 0.80 | HTR1A (0.54) | MAPTMEN1KMT2ASMN1; SMN2KCNH2 | |
| SCHEMBL27513445 | 0.80 | MAPT (0.53) | MAPTMEN1KMT2ASMN1; SMN2KCNH2 | |
| SCHEMBL27540736 | 0.79 | HTR1A (0.53) | MAPTMEN1KMT2ALMNAKCNH2 | |
| SCHEMBL27537453 | 0.79 | KCNH2 (0.50) | MAPTMEN1KMT2ASMN1; SMN2KCNH2 | |
| SCHEMBL27460384 | 0.79 | MAPT (0.59) | MAPTMEN1KMT2ASMN1; SMN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1127493-C | 1-(N-phenylaminoalkyl)-piperazine derivatives substituted at position 2 of phenyl ring | RECORDATI CHEM PHARM (CH) | 2003-11-12 | — | — | CN | disclosed |
| CN-1265654-A | 1-(N-phenylaminoalkyl)-piperazine derivatives substituted at position 2 of phenyl ring | RECORDATI CHEM PHARM (CH) | 2000-09-06 | — | — | CN | disclosed |