Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27513126 | 0.91 | HTR1A (0.54) | HTR1AGFERMEN1KMT2AABCB1 | |
| SCHEMBL27514492 | 0.91 | HTR1A (0.62) | HTR1AGFERMEN1KMT2AABCB1 | |
| SCHEMBL27514798 | 0.88 | HTR1A (0.52) | HTR1AGFERMEN1KMT2AABCB1 | |
| SCHEMBL27513125 | 0.81 | KCNH2 (0.53) | HTR1AGFERMEN1KMT2AMAPT | |
| SCHEMBL6933603 | 0.81 | ADRA1D (0.61) | HTR1AABCB1MAPTALDH1A1IGF1R | |
| SCHEMBL27513445 | 0.80 | MAPT (0.53) | HTR1AGFERMEN1KMT2AABCB1 | |
| SCHEMBL27435293 | 0.79 | MAPT (0.50) | HTR1AGFERMEN1KMT2AMAPT | |
| SCHEMBL27537453 | 0.79 | KCNH2 (0.50) | HTR1AGFERMEN1KMT2AMAPT | |
| SCHEMBL27460384 | 0.79 | MAPT (0.59) | HTR1AGFERMEN1KMT2AMAPT | |
| SCHEMBL27512393 | 0.77 | IGF1R (0.60) | HTR1AGFERMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1265654-A | 1-(N-phenylaminoalkyl)-piperazine derivatives substituted at position 2 of phenyl ring | RECORDATI CHEM PHARM (CH) | 2000-09-06 | — | — | CN | claimed |
| CN-1127493-C | 1-(N-phenylaminoalkyl)-piperazine derivatives substituted at position 2 of phenyl ring | RECORDATI CHEM PHARM (CH) | 2003-11-12 | — | — | CN | disclosed |
| CN-1265654-A | 1-(N-phenylaminoalkyl)-piperazine derivatives substituted at position 2 of phenyl ring | RECORDATI CHEM PHARM (CH) | 2000-09-06 | — | — | CN | disclosed |