Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8A | O60658 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22493432 | 0.84 | GRM2 (0.36) | GRM2ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL22493438 | 0.83 | CNR2 (0.43) | CTSAGAASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL22493894 | 0.79 | SCN9A (0.44) | TRPV3NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL22493472 | 0.77 | TRPV3 (0.43) | TRPV3MAPTKDM4EMEN1POLB | |
| SCHEMBL22864062 | 0.74 | PDE10A (0.43) | ADORA2AMAPTNPC1ALDH1A1GAA | |
| SCHEMBL22493739 | 0.74 | PDE10A (0.49) | TRPV3NPC1GAARAB9AKDM4E | |
| SCHEMBL22480758 | 0.74 | TRPV3 (0.39) | ADORA3TRPV3CTSAMAPTNPC1 | |
| SCHEMBL22493866 | 0.73 | CNR2 (0.39) | TRPV3MAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL26856212 | 0.73 | ADRB1 (0.41) | GRM2ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL17886911 | 0.72 | SMN1; SMN2 (0.46) | ALDH1A1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137506-A1 | COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS | CURASEN THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |