Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 4/20 | 0.50 |
| ▸ | RPA1 | P27694 | 1/20 | 0.50 |
| ▸ | P2RY14 | Q15391 | 7/20 | 0.48 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27436131 | 0.91 | CNR2 (0.47) | MARS1RPA1P2RY14SMN1; SMN2CNR2 | |
| SCHEMBL27432766 | 0.91 | MARS1 (0.50) | MARS1RPA1P2RY14PPP1CAMALT1 | |
| SCHEMBL13926380 | 0.88 | MALT1 (0.57) | P2RY14CNR2CNR1HDAC3HDAC4 | |
| SCHEMBL27413923 | 0.88 | RPA1 (0.53) | MARS1RPA1MALT1 | |
| SCHEMBL8369101 | 0.87 | RPA1 (0.61) | MARS1RPA1P2RY14PPP1CASMN1; SMN2 | |
| SCHEMBL5902998 | 0.86 | CNR2 (0.57) | MARS1RPA1P2RY14PPP1CASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8369717 | 0.85 | CNR2 (0.56) | MARS1RPA1P2RY14PPP1CASMN1; SMN2 | |
| SCHEMBL8046115 | 0.84 | RPA1 (0.63) | MARS1RPA1P2RY14PPP1CASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8369220 | 0.83 | RPA1 (0.62) | MARS1RPA1P2RY14PPP1CASMN1; SMN2 | |
| SCHEMBL27437124 | 0.82 | HDAC3 (0.42) | SMN1; SMN2CNR2CNR1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1101813-C | 3-pyrazolecarboxamide derivs. having cannabinoid receptor affinity | SANOFI SYNTHELABO (FR) | 2003-02-19 | — | — | CN | disclosed |
| CN-1207731-A | 3-pyrazolecarboxamide derivs. having cannabinoid receptor affinity | SANOFI SA (FR) | 1999-02-10 | — | — | CN | disclosed |