Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27411930 | 0.92 | CNR1 (0.49) | CNR1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL8369769 | 0.87 | CNR1 (0.58) | CNR1SMN1; SMN2KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL8364838 | 0.86 | CNR1 (0.57) | CNR1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL27435381 | 0.81 | MARS1 (0.50) | CNR1SMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL8364939 | 0.79 | CNR1 (0.51) | CNR1SMN1; SMN2MAPTCYP2C9GCGR | |
| SCHEMBL8369230 | 0.79 | CNR1 (0.57) | CNR1SMN1; SMN2KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL8364818 | 0.78 | CNR1 (0.50) | CNR1SMN1; SMN2MAPTCYP2C9GCGR | |
| SCHEMBL8364836 | 0.78 | CNR1 (0.61) | CNR1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL8369103 | 0.78 | GCGR (0.48) | CNR1SMN1; SMN2CYP2C9GCGRCYP19A1 | |
| Hydrochloric Acid SCHEMBL8366437 | 0.77 | GCGR (0.47) | CNR1SMN1; SMN2CYP2C9GCGRCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1101813-C | 3-pyrazolecarboxamide derivs. having cannabinoid receptor affinity | SANOFI SYNTHELABO (FR) | 2003-02-19 | — | — | CN | disclosed |
| CN-1207731-A | 3-pyrazolecarboxamide derivs. having cannabinoid receptor affinity | SANOFI SA (FR) | 1999-02-10 | — | — | CN | disclosed |