Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764598 | 0.85 | PTPN1 (0.51) | PTPN1SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL27402220 | 0.81 | PRMT1 (0.48) | SMN1; SMN2ALDH1A1LMNAHPGDCA1 | |
| SCHEMBL27476399 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL12190343 | 0.70 | PTPN1 (0.63) | PTPN1SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL21765873 | 0.68 | PTPN1 (0.88) | PTPN1SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL6767619 | 0.68 | CYP2C19 (0.55) | ALDH1A1LMNAHPGDCA1CA2 | |
| SCHEMBL6769208 | 0.68 | ALDH1A1 (0.52) | ALDH1A1LMNAPOLBCA1CA2 | |
| SCHEMBL6764639 | 0.66 | PRMT1 (0.55) | SMN1; SMN2ALDH1A1LMNAHPGDCA1 | |
| SCHEMBL13167575 | 0.65 | PTPN1 (0.69) | PTPN1SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL10294766 | 0.65 | PTPN1 (0.69) | PTPN1SMN1; SMN2ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1105114-C | Sulfonyl divalent aryl alpha-hydroxamic acid compounds | MANSANTO CO (US) | 2003-04-09 | — | — | CN | disclosed |
| CN-1253559-A | Sulfonyl divalent aryl alpha-hydroxamic acid compounds | MONSANTO CO (US) | 2000-05-17 | — | — | CN | disclosed |