Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | ANPEP | P15144 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936702 | 1.00 | ALDH1A1 (0.58) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL12197317 | 0.88 | POLB (0.59) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL7392765 | 0.86 | POLB (0.70) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL12197316 | 0.86 | POLB (0.58) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL12534426 | 0.86 | ALDH1A1 (0.59) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL9003236 | 0.86 | POLB (0.70) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL5158344 | 0.84 | MME (0.51) | L3MBTL1 | |
| SCHEMBL6821732 | 0.84 | ALDH1A1 (0.57) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL4024431 | 0.84 | POLB (0.63) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL3959739 | 0.83 | ATM (0.68) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1127488-C | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 2003-11-12 | — | — | CN | disclosed |
| CN-1216537-A | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 1999-05-12 | — | — | CN | disclosed |