SCHEMBL27435883 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	HCAR2	Q8TDS4	1/20	0.35

▸	ALDH1A1	P00352	3/20	0.34

▸	MAPK1	P28482	1/20	0.34

▸	SMN1; SMN2	Q16637	1/20	0.34

▸	GPR35	Q9HC97	5/20	0.33

▸	NOTUM	Q6P988	1/20	0.33

▸	KDM4E	B2RXH2	1/20	0.31

▸	HSD17B10	Q99714	1/20	0.31

▸	DPP4	P27487	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL27501454	0.91	HCAR2 (0.35)	HCAR2ALDH1A1MAPK1SMN1; SMN2GPR35
SCHEMBL13154639	0.81	NOTUM (0.38)	HCAR2ALDH1A1MAPK1SMN1; SMN2GPR35
SCHEMBL11223557	0.81	NOTUM (0.41)	HCAR2ALDH1A1MAPK1SMN1; SMN2GPR35
SCHEMBL11654790	0.81	ALDH1A1 (0.41)	HCAR2ALDH1A1MAPK1SMN1; SMN2GPR35
SCHEMBL26841743	0.77	ALDH1A1 (0.39)	HCAR2ALDH1A1MAPK1SMN1; SMN2GPR35
SCHEMBL14507766	0.77	ALDH1A1 (0.39)	HCAR2ALDH1A1MAPK1SMN1; SMN2GPR35
SCHEMBL7821278	0.76	GPR35 (0.39)	ALDH1A1MAPK1SMN1; SMN2GPR35NOTUM
SCHEMBL11678094	0.76	CYP1A2 (0.39)	ALDH1A1MAPK1SMN1; SMN2GPR35KDM4E
SCHEMBL1953847	0.76	ALDH1A1 (0.41)	HCAR2ALDH1A1MAPK1SMN1; SMN2GPR35
SCHEMBL6825425	0.75	DPP4 (0.36)	HCAR2ALDH1A1MAPK1SMN1; SMN2GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-1129003-A	Reduced fluorescence compositions containing naphthalenedicarboxylic acid polymers and halogens	EASTMAN CHEM CO (US)	1996-08-14	—	—	CN	disclosed