Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860592 | 0.90 | PRKDC (0.49) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL1134649 | 0.89 | PRKDC (0.58) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL6782177 | 0.85 | PRKDC (0.47) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL19453679 | 0.85 | PRKDC (0.55) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL20661182 | 0.85 | PRKDC (0.55) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL3152057 | 0.85 | PRKDC (0.58) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL9861378 | 0.84 | ERN1 (0.60) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL9860690 | 0.84 | ERN1 (0.57) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL9016756 | 0.84 | PRKDC (0.53) | PRKDCALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL3751505 | 0.82 | ALDH1A1 (0.59) | PRKDCALDH1A1KDM4ETSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12436135-B2 | Analytical process for detecting peroxide-, nitrate-, nitramine-, and nitrotoluene-based explosives | CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL (DE) | 2025-10-07 | — | — | US | disclosed |
| EP-4073505-A1 | ANALYTICAL PROCESS FOR DETECTING PEROXIDE-, HALOGEN OXOANION-, NITRATE-, NITRAMINE- AND NITROTOLUENE-BASED EXPLOSIVES | Christian-Albrechts-Universität zu Kiel (DE) | 2022-10-19 | — | — | EP | disclosed |
| US-20220308027-A1 | ANALYTICAL PROCESS FOR DETECTING PEROXIDE-, HALOGEN OXOANION-, NITRATE-, NITRAMINE-, AND NITROTOLUENE-BASED EXPLOSIVES | CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL (DE) | 2022-09-29 | — | — | US | disclosed |
| WO-2021198249-A1 | ANALYTICAL PROCESS FOR DETECTING PEROXIDE-, HALOGEN OXOANION-, NITRATE-, NITRAMINE- AND NITROTOLUENE-BASED EXPLOSIVES | CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL (DE) | 2021-10-07 | — | — | WO | disclosed |
| US-10383831-B2 | 2,4,6-trialkoxystryl aryl sulfones, sulfonamides and carboxamides, and methods of preparation and use | Temple University—Of the Commonwealth System of Higher Education (US) | 2019-08-20 | — | — | US | disclosed |
| US-20180243239-A1 | 2,4,6-TRIALKOXYSTRYL ARYL SULFONES, SULFONAMIDES AND CARBOXAMIDES, AND METHODS OF PREPARATION AND USE | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2018-08-30 | — | — | US | disclosed |
| WO-2017023912-A1 | 2,4,6-TRIALKOXYSTRYL ARYL SULFONES, SULFONAMIDES AND CARBOXAMIDES, AND METHODS OF PREPARATION AND USE | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-02-09 | — | — | WO | disclosed |
| CN-106083557-A | α, β unsaturation cyclohexanone derivative and application thereof | 武汉理工大学 | 2016-11-09 | — | — | CN | disclosed |
| US-8637575-B2 | Modulators of protein kinase signaling | NOVOTYR THERAPEUTICS LTD. (IL) | 2014-01-28 | — | — | US | disclosed |
| US-8536227-B2 | — | — | 2013-09-17 | — | — | US | disclosed |
| WO-2006067412-A1 | CHEMICAL PROCESSES FOR THE PREPARATION OF A COLCHINOL DERIVATIVE AND INTERMEDIATES | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |
| WO-2006067416-A1 | CHEMICAL PROCESSES AND INTERMEDIATES | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |
| CN-1475486-A | Chiral 3-aryl benzo phthalein kind compound, synthesis method and use | 中国科学院上海有机化学研究所 | 2004-02-18 | — | — | CN | disclosed |
| US-5731455-A | ALKYL 2-ALKYLACYLACRYLATE CHEMICAL INTERMEDIATE; ANTICHOLESTEROL AGENTS | SHIONOGI & CO., LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| EP-0597107-B1 | LIGNAN ANALOG, PRODUCTION THEREOF, AND HYPOLIPIDEMIC DRUG | SHIONOGI & CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5502216-A | ANTICHOLESTEROL | SHIONOGI & CO., LTD. (JP) | 1996-03-26 | — | — | US | disclosed |
| EP-0701991-A1 | Process for the preparation of lignin analogues and starting materials therefor | SHIONOGI & CO., LTD. (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5449814-A | Dehydration; Michael condensation | SHIONOGI & CO., LTD. (JP) | 1995-09-12 | — | — | US | disclosed |
| US-5420333-A | Hydroxy ketone compounds | SHIONOGI & CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0597107-A1 | LIGNAN ANALOG, PRODUCTION THEREOF, AND HYPOLIPIDEMIC DRUG | SHIONOGI & CO., LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10383831-B2 | 2,4,6-trialkoxystryl aryl sulfones, sulfonamides and carboxamides, and methods of preparation and use | CCNY, STS, ARSA | PRKDC 3236/4885ALDH1A1 1603/4885KDM4E 1855/4885 |
| US-20180243239-A1 | 2,4,6-TRIALKOXYSTRYL ARYL SULFONES, SULFONAMIDES AND CARBOXAMIDES, AND METHODS OF PREPARATION AND USE | CCNY, STS, ARSA | PRKDC 3236/4885ALDH1A1 1603/4885KDM4E 1855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.