Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 13/20 | 0.60 |
| ▸ | PRKDC | P78527 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.46 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860690 | 0.86 | ERN1 (0.57) | ERN1PRKDCKDM4EALDH1A1TSHR | |
| SCHEMBL1646879 | 0.86 | ERN1 (0.64) | ERN1PRKDCKDM4EALDH1A1TSHR | |
| SCHEMBL24140773 | 0.86 | ERN1 (0.64) | ERN1PRKDCKDM4EALDH1A1TSHR | |
| SCHEMBL16093499 | 0.84 | ERN1 (0.62) | ERN1PRKDCKDM4EALDH1A1TSHR | |
| SCHEMBL2743635 | 0.84 | PRKDC (0.58) | ERN1PRKDCKDM4EALDH1A1TSHR | |
| SCHEMBL16385983 | 0.84 | ERN1 (0.67) | ERN1KDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL15534494 | 0.83 | ERN1 (0.73) | ERN1PRKDCKDM4EALDH1A1TSHR | |
| SCHEMBL23094539 | 0.83 | ERN1 (0.60) | ERN1PRKDCKDM4EALDH1A1TSHR | |
| SCHEMBL11999813 | 0.83 | ERN1 (0.61) | ERN1PRKDCKDM4EALDH1A1TSHR | |
| SCHEMBL9016537 | 0.81 | ERN1 (0.58) | ERN1PRKDCKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101050179-B | 2,3,4,5-tetrasubstituted derivatives of benzyl ethylene class, preparation method and application | ZHEJIANG HISUN PHARM CO LTD | 2011-05-11 | — | — | CN | disclosed |
| CN-101050179-A | 2,3,4,5-tetrasubstituted derivatives of benzyl ethylene class, preparation method and application | HAIZHENGTIANHUA NEW MEDICINE R (CN) | 2007-10-10 | — | — | CN | disclosed |
| US-5070103-A | ANTILIPEMIC AGENTS, ARTERIOSCLEROSIS | TANABE SEIYAKU CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |