SCHEMBL27436574

SCHEMBL27436574

CC(C)c1nc(CC(C)c2cocn2)cs1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.39
DRD2 P14416 1/20 0.33
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23328947 0.74 SLC6A3 (0.48) SLC6A3DRD2HTR2AHRH1
SCHEMBL10163704 0.72 SLC6A3 (0.46) SLC6A3DRD2HTR2AHRH1MEN1
SCHEMBL848336 0.70
SCHEMBL9285640 0.69 PIK3CD (0.37) SLC6A3
SCHEMBL2819185 0.67 SLC6A3 (0.47) SLC6A3DRD2HTR2AHRH1MEN1
SCHEMBL9963728 0.67
SCHEMBL18938015 0.66 SLC6A3 (0.41) SLC6A3DRD2HTR2AHRH1
SCHEMBL21501929 0.66 SLC6A3 (0.42) SLC6A3DRD2HTR2AHRH1
SCHEMBL16603147 0.66 SLC6A3 (0.46) SLC6A3DRD2HTR2AHRH1MEN1
SCHEMBL348008 0.66 SLC6A3 (0.46) SLC6A3DRD2HTR2AHRH1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024112830-A1 INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF MAZE THERAPEUTICS, INC. (US) 2024-05-30 WO disclosed