Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20757741 | 0.84 | SLC6A3 (0.45) | SLC6A3TLR7TSHRALDH1A1HTT | |
| SCHEMBL27436574 | 0.74 | SLC6A3 (0.39) | SLC6A3HRH1DRD2HTR2A | |
| SCHEMBL22725661 | 0.74 | TSHR (0.38) | SLC6A3TLR7TSHRKCNA5KCNH2 | |
| SCHEMBL25003875 | 0.72 | TSHR (0.41) | SLC6A3HRH1HTR2ATSHRKCNA5 | |
| SCHEMBL10163704 | 0.72 | SLC6A3 (0.46) | SLC6A3TLR7HRH1DRD2HTR2A | |
| Hydrochloric Acid SCHEMBL4850267 | 0.72 | SLC6A3 (0.51) | SLC6A3TLR7HRH1DRD2HTR2A | |
| SCHEMBL20666526 | 0.71 | ALDH1A1 (0.40) | SLC6A3TSHRNPC1KCNA5KCNH2 | |
| SCHEMBL26278070 | 0.71 | ESR1 (0.45) | SLC6A3HRH1HTR2ATSHRNPC1 | |
| SCHEMBL24199566 | 0.70 | TSHR (0.36) | SLC6A3HRH1HTR2ATSHRKCNA5 | |
| SCHEMBL10249190 | 0.70 | SLC6A3 (0.56) | SLC6A3TLR7HRH1DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210130359-A1 | SULFONYLUREAS AND SULFONYLTHIOUREAS AS NLRP3 INHIBITORS | INFLAZOME LIMITED (IE) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130359-A1 | SULFONYLUREAS AND SULFONYLTHIOUREAS AS NLRP3 INHIBITORS | NLRP3, NOD1, NLRP1 | SLC6A3 1017/4885TLR7 1035/4885HRH1 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.