Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864678 | 0.83 | GAA (0.59) | MEN1KMT2AHPGDALDH1A1GAA | |
| SCHEMBL5865211 | 0.78 | ALOX15 (0.56) | MEN1KMT2AHPGDALDH1A1GAA | |
| SCHEMBL27436187 | 0.76 | PTGER4 (0.43) | MEN1KMT2AHPGDALDH1A1GAA | |
| SCHEMBL23827487 | 0.71 | GAA (0.53) | MEN1KMT2AHPGDALDH1A1GAA | |
| SCHEMBL23567997 | 0.69 | GPR35 (0.78) | MEN1KMT2AHPGDALDH1A1GAA | |
| SCHEMBL23827460 | 0.69 | KMT2A (0.50) | MEN1KMT2AHPGDALDH1A1GAA | |
| SCHEMBL23827479 | 0.68 | HSD17B10 (0.55) | MEN1KMT2AHPGDALDH1A1GAA | |
| SCHEMBL11186472 | 0.68 | NR4A1 (0.63) | MEN1KMT2AHPGDCOPS5TDP1 | |
| SCHEMBL5105542 | 0.68 | MAPT (0.56) | MEN1KMT2AHPGDALDH1A1GAA | |
| SCHEMBL27531649 | 0.68 | NR4A1 (0.53) | MEN1KMT2AHPGDTDP1NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1122037-C | Thieno [2, 3-d ] pyrimidinediones, preparation method and use thereof, and pharmaceutical compositions containing the same | ASTRA PHARMA PROD (GB) | 2003-09-24 | — | — | CN | disclosed |
| CN-1264382-A | Novel compounds | ASTRA PHARMA PROD (GB) | 2000-08-23 | — | — | CN | disclosed |