SCHEMBL27437833

SCHEMBL27437833

CCCCOC(=O)C(O)(CC)CN

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
ATM Q13315 1/20 0.42
TSHR P16473 6/20 0.40
HPGD P15428 1/20 0.40
HCAR2 Q8TDS4 1/20 0.38
LMNA P02545 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
PDE4D Q08499 1/20 0.38
HTR2C P28335 1/20 0.38
NAAA Q02083 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HSD17B10 Q99714 1/20 0.36
EPHX1 P07099 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28943705 0.81 CYP1A2 (0.39) ALDH1A1ATMTSHRHPGDCYP1A2
SCHEMBL28260707 0.78 NAAA (0.46) ALDH1A1ATMTSHRHCAR2LMNA
SCHEMBL27427377 0.77 ALDH1A1 (0.41) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL5622465 0.77 ALDH1A1 (0.48) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL1734681 0.76 NAAA (0.48) ALDH1A1ATMTSHRHCAR2LMNA
SCHEMBL20704238 0.76 HCAR2 (0.39) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL13839035 0.76 ALDH1A1 (0.56) ALDH1A1ATMTSHRHPGDHCAR2
Tributyl Citrate SCHEMBL9712117 0.76 NAAA (0.47) ALDH1A1ATMTSHRHPGDHCAR2
Tributyl Citrate SCHEMBL24668 0.76 NAAA (0.47) ALDH1A1ATMTSHRHPGDHCAR2
SCHEMBL28823876 0.76 ALDH1A1 (0.47) ALDH1A1ATMTSHRHPGDHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108395413-B A kind of preparation method of morpholine -3- carboxylic acid 上海馨远医药科技有限公司 2019-05-28 CN claimed
CN-108395413-A A kind of preparation method of morpholine -3- carboxylic acids 上海馨远医药科技有限公司 2018-08-14 CN claimed
CN-102731777-B Synthesis method of poly-benzyl L-glutamate/ethyl polyphosphate block copolymer UNIV LIAONING 2013-12-18 CN claimed
CN-102731777-A Synthesis method of poly-benzyl L-glutamate/ethyl polyphosphate block copolymer UNIV LIAONING 2012-10-17 CN claimed
CN-108395413-B A kind of preparation method of morpholine -3- carboxylic acid 上海馨远医药科技有限公司 2019-05-28 CN disclosed
CN-108395413-B A kind of preparation method of morpholine -3- carboxylic acid 上海馨远医药科技有限公司 2019-05-28 CN disclosed
CN-108395413-A A kind of preparation method of morpholine -3- carboxylic acids 上海馨远医药科技有限公司 2018-08-14 CN disclosed
CN-108395413-A A kind of preparation method of morpholine -3- carboxylic acids 上海馨远医药科技有限公司 2018-08-14 CN disclosed
CN-104788405-B Aromatic polycyclic carboxylic acid derivatives 山东轩竹医药科技有限公司 2017-04-19 CN disclosed
CN-104788412-B Aromatic polycyclic carboxylic acid derivatives 山东轩竹医药科技有限公司 2017-02-15 CN disclosed
CN-104788412-A Aromatic polycyclic carboxylic acid derivatives KBP BIOSCIENCES CO LTD 2015-07-22 CN disclosed
CN-104788405-A Aromatic polycyclic carboxylic acid derivatives KBP BIOSCIENCES CO LTD 2015-07-22 CN disclosed
CN-102731777-B Synthesis method of poly-benzyl L-glutamate/ethyl polyphosphate block copolymer UNIV LIAONING 2013-12-18 CN disclosed
CN-102731777-A Synthesis method of poly-benzyl L-glutamate/ethyl polyphosphate block copolymer UNIV LIAONING 2012-10-17 CN disclosed
CN-1098843-C Isoxazoles SANKYO CO (JP) 2003-01-15 CN disclosed
CN-1162957-A Isoxazole derivatives SANKYO CO (JP) 1997-10-22 CN disclosed