Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 11/20 | 0.50 |
| ▸ | CA2 | P00918 | 11/20 | 0.50 |
| ▸ | CA9 | Q16790 | 8/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27476512 | 1.00 | MEN1 (0.58) | MEN1THRBHTTKMT2AMAPT | |
| Sulfuric Acid SCHEMBL4934147 | 0.93 | MEN1 (0.60) | MEN1THRBHTTKMT2AMAPT | |
| Sulfuric Acid SCHEMBL9696774 | 0.93 | MEN1 (0.60) | MEN1THRBHTTKMT2AMAPT | |
| Sulfuric Acid SCHEMBL343673 | 0.93 | MEN1 (0.60) | MEN1THRBHTTKMT2AMAPT | |
| Sulfuric Acid SCHEMBL316834 | 0.93 | MEN1 (0.60) | MEN1THRBHTTKMT2AMAPT | |
| Sulfuric Acid SCHEMBL2148238 | 0.93 | MEN1 (0.60) | MEN1THRBHTTKMT2AMAPT | |
| Sulfuric Acid SCHEMBL94784 | 0.93 | MEN1 (0.60) | MEN1THRBHTTKMT2AMAPT | |
| Sulfuric Acid SCHEMBL2935714 | 0.93 | MEN1 (0.60) | MEN1THRBHTTKMT2AMAPT | |
| Sulfuric Acid SCHEMBL8596252 | 0.93 | MEN1 (0.60) | MEN1THRBHTTKMT2AMAPT | |
| Sulfuric Acid SCHEMBL9547095 | 0.93 | MEN1 (0.60) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1105158-C | Carbon products, inks and coatings containing the same and methods of using the same to improve optical properties | CABOT CORP (US) | 2003-04-09 | — | — | CN | disclosed |
| CN-1175271-A | Non-aqueous inks and coatings containing carbon products | CABOT CORP (US) | 1998-03-04 | — | — | CN | disclosed |