Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27460820 | 0.91 | GRIN2B (0.52) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL27459644 | 0.86 | GRIN2B (0.62) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL8542871 | 0.81 | GRIN2B (0.54) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL27391248 | 0.79 | GRIN2B (0.56) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL27460009 | 0.74 | GRIN2B (0.64) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL27459289 | 0.74 | GRIN2B (0.54) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL8544030 | 0.73 | GRIN2B (0.55) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL28964579 | 0.72 | GRIN2B (0.44) | GRIN2BCCR3OPRM1 | |
| SCHEMBL8892949 | 0.72 | GRIN2B (0.71) | GRIN2BGRIN1GMNNTP53CYP3A4 | |
| SCHEMBL8547312 | 0.72 | MAOA (0.54) | GRIN2BGRIN1GRIN2DGRIN3BADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1128762-A | Benzyl piperidine derivatives | MERCK PATENT GMBH (DE) | 1996-08-14 | — | — | CN | disclosed |