Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28069971 | 0.82 | MGAM (0.38) | KDM4EATMRAB9ACYP1A2CYP2D6 | |
| SCHEMBL28178444 | 0.80 | LMNA (0.39) | KMT2ASMN1; SMN2RECQLALOX15KDM4E | |
| SCHEMBL9093356 | 0.80 | — | — | |
| SCHEMBL27341667 | 0.76 | SMN1; SMN2 (0.51) | KMT2ASMN1; SMN2RECQLCYP19A1ALDH1A1 | |
| SCHEMBL28463194 | 0.76 | KDM4E (0.35) | KMT2AKDM4EATMRAB9ACYP1A2 | |
| SCHEMBL11346091 | 0.75 | — | — | |
| SCHEMBL28206765 | 0.74 | ALDH1A1 (0.38) | SMN1; SMN2KDM4EATMRAB9AACHE | |
| SCHEMBL27969532 | 0.74 | TDP1 (0.51) | KMT2ASMN1; SMN2KDM4ECYP1A2CYP2C9 | |
| SCHEMBL28924739 | 0.73 | KMT2A (0.43) | KMT2ASMN1; SMN2ELANERAB9ANPC1 | |
| SCHEMBL11214113 | 0.73 | KMT2A (0.45) | KMT2ASMN1; SMN2KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715194-A | For treating the Gene reelin proteinase composition of neurological disorder | 南佛罗里达大学 | 2019-05-03 | — | — | CN | disclosed |
| CN-107304183-A | Pyrrole Lun Panai crystal formations and its production and use | 扬子江药业集团上海海尼药业有限公司 | 2017-10-31 | — | — | CN | disclosed |
| CN-107109413-A | The rna editing of targeting | ProQR治疗上市公司Ⅱ | 2017-08-29 | — | — | CN | disclosed |
| CN-1121921-A | New benzothiadiazine compound, process for its preparation and the pharmaceutical compositions which contain it | ADIR (FR) | 1996-05-08 | — | — | CN | disclosed |
| CN-1122136-A | Benzo[f]quinoxalindione derivatives, their preparation and their use in drugs | SCHERING AG (DE) | 1996-05-08 | — | — | CN | disclosed |
| CN-1121720-A | Pyrido(1,2,3-de)quinoxaline derivatives, process for preparing the same and their use in medicaments | SCHERING AG (DE) | 1996-05-01 | — | — | CN | disclosed |