Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 13/20 | 0.61 |
| ▸ | TNKS | O95271 | 11/20 | 0.61 |
| ▸ | PARP1 | P09874 | 7/20 | 0.61 |
| ▸ | WNT3A | P56704 | 7/20 | 0.61 |
| ▸ | PARP2 | Q9UGN5 | 6/20 | 0.61 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.61 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.61 |
| ▸ | AXIN2 | Q9Y2T1 | 1/20 | 0.61 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.61 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | COMT | P21964 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27438538 | 0.88 | TNKS2 (0.58) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL7783488 | 0.76 | TNKS2 (1.00) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL30870719 | 0.74 | TNKS2 (0.78) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL15565864 | 0.68 | TNKS2 (0.67) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL27438107 | 0.64 | TNKS2 (0.82) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL27438444 | 0.64 | TNKS2 (0.80) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL11284110 | 0.64 | TNKS (1.00) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL30870677 | 0.63 | TNKS2 (0.75) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL7013457 | 0.63 | RAB9A (0.59) | TNKS2TNKSPARP1WNT3APARP2 | |
| SCHEMBL2433653 | 0.63 | COMT (1.00) | TNKS2TNKSPARP1WNT3APARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024086246-A2 | 2-SUBSTITUTED 3,4 A, 5, 7, 8, 8 A-HEXAHYDRO-4H-THIOP YRANO [4,3- DJPYRIMIDIN-4-ONES FOR WOUND TREATMENT | Eluciderm Inc. (US) | 2024-04-25 | — | — | WO | disclosed |