Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31272586 | 0.85 | CA1 (0.47) | LMNARECQLPRSS1PRSS2PRSS3 | |
| SCHEMBL1962748 | 0.85 | CA1 (0.47) | LMNARECQLPRSS1PRSS2PRSS3 | |
| SCHEMBL12955914 | 0.85 | CA1 (0.47) | LMNARECQLPRSS1PRSS2PRSS3 | |
| SCHEMBL8982625 | 0.85 | CA1 (0.47) | LMNARECQLPRSS1PRSS2PRSS3 | |
| SCHEMBL16415818 | 0.83 | CA2 (0.46) | LMNARECQLPRSS1PRSS2PRSS3 | |
| SCHEMBL27797254 | 0.83 | KDM4E (0.31) | LMNARECQLALDH1A1TSHR | |
| SCHEMBL28069731 | 0.82 | CYP3A4 (0.46) | LMNARECQLPRSS1PRSS2PRSS3 | |
| SCHEMBL16759507 | 0.82 | CYP3A4 (0.46) | LMNARECQLPRSS1PRSS2PRSS3 | |
| SCHEMBL28272444 | 0.82 | CYP3A4 (0.46) | LMNARECQLPRSS1PRSS2PRSS3 | |
| SCHEMBL28142509 | 0.80 | CYP3A4 (0.47) | LMNARECQLPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1056602-C | Esters and amides as PLA2 inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-09-20 | — | — | CN | disclosed |
| CN-1197450-A | Esters and amides as phospholipase A2 inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-10-28 | — | — | CN | disclosed |