Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | CNR2 | P34972 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19291537 | 0.88 | HPGD (0.54) | CNR1CNR2CYP2D6KCNH2HPGD | |
| SCHEMBL2208515 | 0.88 | CNR1 (0.52) | CNR1CNR2CYP2D6PPARAPPARG | |
| SCHEMBL29818817 | 0.88 | CNR1 (0.52) | CNR1CNR2CYP2D6PPARAPPARG | |
| SCHEMBL27996233 | 0.85 | HPGD (0.60) | CNR1CNR2CYP2D6HPGDHDAC1 | |
| SCHEMBL4568866 | 0.85 | PPARA (0.59) | CNR1CNR2CYP2D6PPARAPPARG | |
| SCHEMBL27439170 | 0.85 | KMT2A (0.55) | HPGD | |
| SCHEMBL612170 | 0.85 | CNR2 (0.56) | CNR1CNR2CYP2D6PPARAPPARG | |
| SCHEMBL7557375 | 0.83 | CNR1 (0.55) | CNR1CNR2CYP2D6KCNH2HPGD | |
| SCHEMBL4568886 | 0.82 | CYP2D6 (0.67) | CNR1CNR2CYP2D6PPARAPPARG | |
| SCHEMBL3028644 | 0.81 | CYP2D6 (0.73) | CYP2D6PPARAPPARGKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029708-B2 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2024-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12029708-B2 | Alkoxy compounds for disease treatment | ALDH1A2, CLN6, AGER | CNR1 2237/4885CNR2 2271/4885CYP2D6 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.