Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8633111 | 0.86 | ACE (0.61) | ACE | |
| SCHEMBL29443075 | 0.86 | ACE (0.61) | ACE | |
| SCHEMBL28162113 | 0.84 | ACE (0.60) | ACE | |
| SCHEMBL29697839 | 0.83 | NOTUM (0.66) | ACE | |
| SCHEMBL2830596 | 0.83 | NOTUM (0.66) | ACE | |
| SCHEMBL31207052 | 0.83 | NOTUM (0.66) | ACE | |
| SCHEMBL2824809 | 0.83 | NOTUM (0.66) | ACE | |
| SCHEMBL2824813 | 0.83 | NOTUM (0.66) | ACE | |
| SCHEMBL30745240 | 0.83 | NOTUM (0.66) | ACE | |
| SCHEMBL4112978 | 0.82 | LMNA (0.58) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438031-A | N-(Alkylsulfonyl)-L-proline amide and N-(alkylsulfonyl)-2-carboxylic acid amide-indoline derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-03-20 | — | — | US | disclosed |