Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.55 |
| ▸ | PGR | P06401 | 2/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286644 | 0.85 | AR (0.53) | ARPGRKDM4EUSP2ALDH1A1 | |
| SCHEMBL7629786 | 0.84 | AR (0.56) | ARPGRCHEK1KDM4EUSP2 | |
| SCHEMBL34471191 | 0.83 | AR (0.55) | ARPGRCHEK1KDM4EUSP2 | |
| SCHEMBL34472219 | 0.83 | AR (0.55) | ARPGRCHEK1KDM4EUSP2 | |
| SCHEMBL21963833 | 0.80 | AR (0.74) | ARPGRKDM4EUSP2ALDH1A1 | |
| SCHEMBL16158532 | 0.80 | AR (0.52) | ARPGRCHEK1KDM4EUSP2 | |
| SCHEMBL9951140 | 0.79 | AR (0.56) | ARPGRCHEK1KDM4EUSP2 | |
| SCHEMBL393816 | 0.78 | ALDH1A1 (0.61) | ARKDM4EUSP2ALDH1A1 | |
| SCHEMBL29964800 | 0.78 | ALDH1A1 (0.61) | ARKDM4EUSP2ALDH1A1 | |
| SCHEMBL20699887 | 0.77 | PDE4A (0.53) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024086246-A2 | 2-SUBSTITUTED 3,4 A, 5, 7, 8, 8 A-HEXAHYDRO-4H-THIOP YRANO [4,3- DJPYRIMIDIN-4-ONES FOR WOUND TREATMENT | Eluciderm Inc. (US) | 2024-04-25 | — | — | WO | disclosed |