Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | FABP7 | O15540 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24476682 | 0.85 | AR (0.54) | ARPGRALDH1A1KDM4EUSP2 | |
| SCHEMBL27439715 | 0.84 | AR (0.55) | ARPGRCHEK1ALDH1A1KDM4E | |
| SCHEMBL34472219 | 0.84 | AR (0.55) | ARPGRCHEK1ALDH1A1KDM4E | |
| SCHEMBL34471191 | 0.84 | AR (0.55) | ARPGRCHEK1ALDH1A1KDM4E | |
| SCHEMBL7282985 | 0.82 | ALDH1A1 (0.71) | CHEK1ALDH1A1KDM4EUSP2ACLY | |
| SCHEMBL16158532 | 0.81 | AR (0.52) | ARPGRCHEK1ALDH1A1KDM4E | |
| SCHEMBL27439951 | 0.81 | KIT (0.46) | ARPGRCHEK1ALDH1A1ACLY | |
| SCHEMBL30870706 | 0.81 | KIT (0.46) | ARPGRCHEK1ALDH1A1ACLY | |
| SCHEMBL9951140 | 0.80 | AR (0.56) | ARPGRCHEK1ALDH1A1KDM4E | |
| SCHEMBL13802320 | 0.79 | AR (0.50) | ARALDH1A1KDM4EACLYCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1102738-B1 | METHOD FOR THE ACIDIC OR ALKALINE SAPONIFICATION OF BIPHENYL NITRILES | LEHMANN BERND DR (DE) | 2002-12-04 | — | — | EP | disclosed |
| EP-1102738-A1 | METHOD FOR THE ACIDIC OR ALKALINE SAPONIFICATION OF BIPHENYL NITRILES | Great Lakes Chemical Konstanz GmbH (DE) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000003964-A1 | METHOD FOR THE ACIDIC OR ALKALINE SAPONIFICATION OF BIPHENYL NITRILES | GREAT LAKES CHEMICAL KONSTANZ GMBH (DE) | 2000-01-27 | — | — | WO | disclosed |