Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27463100 | 0.81 | NR5A1 (0.38) | CA12CA1CA2CA3CA4 | |
| SCHEMBL7198797 | 0.80 | TSHR (0.40) | CA12CA1CA2CA3CA4 | |
| SCHEMBL27461739 | 0.80 | NR5A1 (0.37) | CA12CA1CA2CA3CA4 | |
| SCHEMBL7203576 | 0.80 | NR5A1 (0.40) | NR5A1TSHRTP53LTA4HPLA2G4B | |
| SCHEMBL7204133 | 0.74 | CNR2 (0.41) | — | |
| SCHEMBL5106446 | 0.66 | MAOB (0.50) | NR5A1TSHRTP53LTA4HTHRA | |
| SCHEMBL8630858 | 0.66 | ALDH1A1 (0.51) | CA12CA1CA2CA3CA4 | |
| SCHEMBL6022241 | 0.66 | THRA (0.48) | NR5A1TSHRTP53LTA4HTHRA | |
| SCHEMBL1443663 | 0.66 | ALDH1A1 (0.69) | NR5A1TSHRTP53LTA4HPLA2G4B | |
| SCHEMBL8749655 | 0.65 | MAOB (0.52) | NR5A1TSHRTP53THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1139584-C | Heterocyclic compounds, method for preparing and medicine compositions containing same | ɪά��ʵ���� | 2004-02-25 | — | — | CN | disclosed |