Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 6/20 | 0.72 |
| ▸ | APP | P05067 | 6/20 | 0.72 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27440181 | 0.91 | SNCA (0.76) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL24163776 | 0.91 | APP (0.60) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL27440660 | 0.90 | APP (0.59) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL27440679 | 0.89 | APP (0.58) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL27440633 | 0.86 | APP (0.54) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL24164292 | 0.85 | SNCA (0.66) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL27440741 | 0.84 | APP (0.52) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL24164296 | 0.83 | APP (0.64) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL26118424 | 0.83 | SNCA (0.64) | SNCAAPPENPP2ALDH1A1LMNA | |
| SCHEMBL27440345 | 0.83 | APP (0.60) | SNCAAPPENPP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145369-A1 | COMPOUNDS FOR TREATMENT OF HAIR LOSS | PELAGE PHARMACEUTICALS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |