Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.60 |
| ▸ | SNCA | P37840 | 5/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24164296 | 0.91 | APP (0.64) | APPSNCAENPP2CNR1CNR2 | |
| SCHEMBL27440509 | 0.91 | SNCA (0.72) | APPSNCAENPP2CNR1CNR2 | |
| SCHEMBL27440660 | 0.85 | APP (0.59) | APPSNCAENPP2CNR1CNR2 | |
| SCHEMBL27440741 | 0.85 | APP (0.52) | APPSNCAENPP2MAPTALDH1A1 | |
| SCHEMBL27440679 | 0.84 | APP (0.58) | APPSNCAENPP2MAPTMEN1 | |
| SCHEMBL27440633 | 0.83 | APP (0.54) | APPSNCAENPP2CNR1CNR2 | |
| SCHEMBL27440181 | 0.82 | SNCA (0.76) | APPSNCAENPP2CNR1CNR2 | |
| SCHEMBL24163770 | 0.82 | SNCA (0.62) | APPSNCAENPP2CNR1CNR2 | |
| SCHEMBL17968554 | 0.82 | ENPP2 (0.74) | APPSNCAENPP2CNR1CNR2 | |
| SCHEMBL17968556 | 0.82 | ENPP2 (0.74) | APPSNCAENPP2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022006040-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-01-06 | — | — | WO | disclosed |