Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.58 |
| ▸ | SNCA | P37840 | 5/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27440345 | 0.92 | APP (0.60) | APPSNCAENPP2ALDH1A1MEN1 | |
| SCHEMBL27440660 | 0.90 | APP (0.59) | APPSNCAENPP2ALDH1A1MEN1 | |
| SCHEMBL27440509 | 0.89 | SNCA (0.72) | APPSNCAENPP2ALDH1A1MEN1 | |
| SCHEMBL27440633 | 0.87 | APP (0.54) | APPSNCAENPP2ALDH1A1MEN1 | |
| SCHEMBL24163776 | 0.84 | APP (0.60) | APPSNCAENPP2ALDH1A1MEN1 | |
| SCHEMBL27440741 | 0.81 | APP (0.52) | APPSNCAENPP2ALDH1A1MAPT | |
| SCHEMBL27440682 | 0.81 | SNCA (0.56) | APPSNCAENPP2ALDH1A1MAPT | |
| SCHEMBL27440336 | 0.81 | SNCA (0.63) | APPSNCAENPP2ALDH1A1MEN1 | |
| SCHEMBL24164332 | 0.81 | APP (0.60) | APPSNCAENPP2ALDH1A1MAPT | |
| SCHEMBL27440181 | 0.81 | SNCA (0.76) | APPSNCAENPP2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145369-A1 | COMPOUNDS FOR TREATMENT OF HAIR LOSS | PELAGE PHARMACEUTICALS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |